2010 Bugatti Veyron
The 2010 Bugatti Veyron has a 8.0L V16 engine and gets 8 miles per gallon in the city and 14 miles per gallon on the highway.
Miles-per-gallon.com estimates that it would cost $5,445 per year to fuel the Veyron using today's average gas prices.
*EPA Assumptions: 15,000 miles per year (55% city, 45% highway). $3.60/gallon regular or $3.70/gallon premium.