Best midsize gas mileage - 10 cylinder engine
EPA designations: Midsize Cars
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| Year | Model | Engine | Trans | MPG |
|---|---|---|---|---|
| 2010 | Audi S6 | 5.2L V10 | Auto(S6) | 16 MPG |
| 2011 | Audi S6 | 5.2L V10 | Auto(S6) | 16 MPG |
| 2010 | BMW M5 | 5.0L V10 | Auto(S7) | 13 MPG |
| 2010 | BMW M5 | 5.0L V10 | Manual(M6) | 13 MPG |